Developmental Brain Disorder Gene Database

A curated resource for researchers & clinicians providing genotype and phenotype data from six neurodevelopmental disorders obtained from published literature.

Intellectual Disability Autism Attention Deficit Hyperactivity Disorder Schizophrenia Bipolar Disorder Epilepsy


Missense Variants

Last Updated: May 01, 2021 Total Cases: 3154 Total Genes: 707
Submit Cases

Investigators are encouraged to submit cases for inclusion in the Developmental Brain Disorder Gene Database.

To submit cases for review, please contact the site curator at:

Download Data

Data is made freely available for research purposes. However, if this data is used in a publication, we request you cite our article about this database in JAMA Psychiatry.

Download full LoF summary data as a CSV file (from the LoF variant table)
Download full missense summary data as a CSV file (from the missense variant table)
Download full database as a CSV file (all cases for all genes)

Additional Information:

The Developmental Brain Disorder Gene Database is based on research presented in:
A Cross-Disorder Method to Identify Novel Candidate Genes for Developmental Brain Disorders (JAMA Psychiatry, March 2016)

Visit External Resources:
SFARI gene
DDG2P Database
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