Developmental Brain Disorder Gene Database
- Unique Cases:
- ID, ASD, EP, ADHD, SCZ
- Last Updated:
- September 1, 2022
- Gene Function
- Mediates transport of gamma-aminobutyric acid (GABA) together with sodium and chloride and is responsible for the reuptake of GABA from the synapse (PubMed:30132828). The translocation of GABA, however, may also occur in the reverse direction leading to the release of GABA (By similarity). The direction and magnitude of GABA transport is a consequence of the prevailing thermodynamic conditions, determined by membrane potential and the intracellular and extracellular concentrations of Na(+), Cl(-... (Source: Uniprot)
- Previous symbols
- No previous symbols
- Alias symbols
- GAT1, GABATR, GABATHG, GAT-1, hGAT-1
- Chromosomal Location
- Genomic Coordinates
- Associated Disorders
- Intellectual Disability, Autism, Epilepsy, Attention Deficit Hyperactivity Disorder
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